This is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease.
Clevio Nobrega has his BSc in Biology from the University of Madeira and completed a PhD in Molecular Biology and Cytogenetics from the University of Barcelona in 2007. His post-doc training was at the Center for Neuroscience and Cell Biology in Portugal.
1. Gene and Cell therapy overview.- 2. Gene and Cell therapy history.- 3. Delivery systems for gene therapy.- 4. Stem-cells and tissue regeneration theories.- 5. Gene therapy strategies.- 6. Gene and cell therapy applications.- 7. Gene therapy clinical trials.- 8. Research in gene therapy: celllular and animal models.- 9. Future challenges in gene and cell therapy