Fundamentals of Cage Wash Operations

James D. Cox has a BS in Animal Science from Virginia Tech and a Masters in Laboratory Animal Science from Drexel University. He spent two years working in a breast cancer research lab at the University of Pennsylvania and managed research animal facilities for 17 years at the following institutions; Georgetown University, Walter Reed Army Institute for Research, and the Howard Hughes Medical Institute Janelia Research Campus. For the past 12 years at HHMI, Jim has led a team of individuals in building the animal care and use program from scratch. This work has included guiding the program through four AAALAC accreditation site visits. Currently Jim is responsible for all animal and biological services at Janelia, including rodents, aquatics, drosophila, molecular biology, cell culture, histology, quantitative genomics, and viral services. He has served on multiple AALAS committees, ILAM and ERC, and served as the co‐editor for the LAMA Review for the Lab Animal Management Association. He is currently on the Board of Directors for Americans for Medical Progress, and biomedical research advocacy organization. His unwavering commitment to excellence and innovation has established him as a respected authority in the scientific community, dedicated to supporting and advancing cutting-edge research.Bruce W. Kennedy, IACUC Administrator received his BS degree in zoology and MS in avian sciences at the University of California, Davis, and his EdD in educational leadership at California State Polytechnic University, Pomona (CPP). His career has been a mix of animals, chemistry, training, and people, in research and academic institutions starting in California and included 19 years in Virginia and Maryland. The work has included conducting and managing studies with experimental animals in the disciplines of nutrition, physiology, and developmental biology. Bruce's start in lab animal science was when he used the coturnix quail animal model for his MS graduate thesis in nutritional toxicology. He has also worked at the bench (analytical chemistry) with dogs in protein metabolism and rats in carbohydrate nutrition studies (USDA). He has experience writing Good Laboratory Practice toxicology reports (Hazleton), preparing experimental diets with test substances (FDA), and managing mouse facilities (NIH and Caltech). Bruce was responsible for regulatory compliance at CPP, administering both the animal care and use and the human subjects research committees and assisting graduate students and PIs in their research efforts. Currently he is the IACUC administrator at Chapman University and a lecturer on lab animal science at CPP. After earning his Laboratory Animal Technologist certification from AALAS, he inaugurated a lab animal training course for the USDA. He holds both the Certified Manager of Animal Resources and the Certified Professional IACUC Administrator certifications. He is past president of the Laboratory Animal Welfare Training Exchange (and will be 2018/9 treasurer) and American Association of Laboratory Animal Science (AALAS). He served on the AALAS education, certification, and the scientific advisory committees. Bruce is a director of the California Society for Biomedical Research and a recipient of the B&K Institute of Animal Technology scholarship, the AALAS George R. Collins award for training and educating in laboratory animal science, and the Purina LabDiet animal technician award. He has served as an ad hoc specialist with AAALAC International.

• Section 1 – Origins and Foundations 1. Cage Wash – It's No Longer Entry Level 2. Cage Wash History, Evolution, and General Cage Wash Management Concepts 3. Laws and Regulations Impacting Cage Wash Operations Section 2 – Persons Working in Cage Wash 4. The Changing Job of Cage Wash Technicians 5. Managing the Cage Wash Facility 6. Safety Considerations Associated with Cage Wash Operations 7. Training and Developing the Support Team in Cage Wash Operations Section 3 – Design and Infrastructure of Cage Washrooms 8. Cage Wash Facility Design Concepts 9. Utility Requirements for Cage Washing and Processing Section 4 – Machines, Equipment, Materials, and Maintenance 10. Cage Washing Machines 11. Sterilizing Machines 12. Automation in Cage Wash 13. Other Equipment, Machines, and Components 14. Maintenance and Troubleshooting of Washers and Sterilizers Section 5 – Diverse Processes of Cage Wash Operations 15. Equipment to be Cleaned and the Cleaning Process 16. Chemicals in Cage Wash: Types, Uses, and Dispensing 17. Waste Processing and Discharge from Cage Washing Facilities 18. Recordkeeping in Cage Wash Operations 19. Disaster, Contingency, and Business Recovery Planning for Animal Facility Cage Wash Operations Section 6 - What's Next in Cage Wash 20. Looking Ahead Appendix: Case Studies. Glossary