Evolution of the Protein Synthesis Machinery and Its Regulation

Häftad, Engelska, 2018

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The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective.

Produktinformation

Utgivningsdatum2018-04-22
Mått155 x 235 x undefined mm
Vikt861 g
FormatHäftad
SpråkEngelska
Antal sidor564
FörlagSpringer International Publishing AG
ISBN9783319818931

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Greco Hernández, PhD.Division of Basic ResearchNational Institute for Cancer (INCan)22 San Fernando Ave.Tlalpan. 14080 Mexico City, MexicoPhone: +52/55/56 28 04 33Fax: +52/55/51 71 05 30Email: greco.hernandez@gmail.comRosemary JagusInstitute of Marine and Environmental TechnologyUniversity of Maryland Center for Environmental Science701 E. Pratt StreetBaltimore MD 21202, U.S.Email: jagus@umces.edu

A review on the origin of the different codes for translation.- Evolution of ribosomes.- Origins and early evolution of ribosomes.- Evolution of ribosomes and ribosomal proteins.- Evolution of Class II aminoacyl synthetases from the antisense of the genes for Class I.- The translation process during the evolutionary transition from prokaryotes to eukaryotes.- Evolution of translational control: from archaea to eukarya.- Distribution of elongation family GTPases EF1A and EFL in basal alveolate lineages.- Evolution of mRNA structure; the eukaryotic mRNA 5´- and 3´- untranslated regions and their role in translational regulation.- How lower eukaryotes contribute on our understanding of eIF4E-dependent translation.- Evolution of functionally divergent eIF4Es and their roles in the regulation of mRNA recruitment and developmental processes.- Evolution of eIF4E and eIF4G interactions in trypanosomes.- Evolution of the functionally divergent eIF4E family members in deuterostomes.- Evolution of the eIF2alpha kinases and translational control.- Evolution and use of eIF2alpha kinases in the apicomplexans and their role in life history of the parasites Plasmodium falciparum and Toxoplasma gondii.- Evolution of the TOR pathway and translational regulation.- Origin and diversification of eIF4E-binding proteins.- Evolution of the protein synthesis machinery in mitochondria.- Relationship between plant translation initiation factors and RNA viruses: An evolutionary perspective.- Evolution of miRNAs and RNA binding proteins in eukaryotes.- Evolution of silencing foci across eukaryotes.- Evolutionary conservation of the machineries coupling RNA transport with translation in eukaryotes.