DJ-1/PARK7 Protein

Parkinson’s Disease, Cancer and Oxidative Stress-Induced Diseases

Häftad, Engelska, 2018

Av Hiroyoshi Ariga, Sanae M. M. Iguchi-Ariga, Sanae M. M. Iguchi-Ariga

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This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases. Those chapters present the roles of DJ-1 in various oxidative stress-related diseases such as neurodegenerative diseases, as well as cancer, diabetes, and fertility.

Produktinformation

Utgivningsdatum2018-12-12
Mått155 x 235 x 12 mm
Vikt401 g
FormatHäftad
SpråkEngelska
SerieAdvances in Experimental Medicine and Biology
Antal sidor222
FörlagSpringer Verlag, Singapore
ISBN9789811349089

Tillhör följande kategorier

Onkologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik

Preface.-　Chapter 1 Introduction/Overview.- Chapter 2 Structural Biology of the DJ-1 Superfamily.- Chapter 3 Expression of DJ-1 in patients with neurodegenerative diseases.- Chapter 4 DJ-1 as an oncogene and its clinical significance.- Chapter 5 Role of DJ-1 in fertilization.- Chapter 6 Anti-oxidative stress function of DJ-1.- Chapter 7 Ttranscriptional regulation of DJ-1.- Chapter 8 Regulation of Signal Transduction by DJ-1.- Chapter 9 Protein repair by DJ-1 from glycation by glyoxal and methylglyoxal.- Chapter 10 DJ-1 as a biomarker of Parkinson's disease.- Chapter 11 Roles of DJ-1 in diabetes mellitus .- Chapter 12 Therapeutic activities of DJ-1 and its binding compounds against neurodegenerative diseases.- Chapter 13 DJ-1 as an oncogene and promising target for cancer chemotherapy.