Directed Drug Delivery

Because the delivery of precise quantities of drugs to specific sites on an optimal schedule is one of the most complex problems in clinical pharmacology and therapeutics today, Borchardt, Repta and Stella have striven to organize in this text a wide-ranging review of the subject. Coverage of nearly all of the key physical, chemical, and biological aspects of targeted drug delivery is provided by an internationally prominent cadre of authors, and includes treatment of: pharmacodynamics; pharmocokinetic factors; molecular mechanisms; therapeutic variables; receptors and delivery; "in vivo" electrochemistry; chromatographic analysis; microparticulate carriers; biodegradable systems; macromolecular systems; monoclonal antibody carriers; prodrugs; scintigraphy; physicochemical variables; the GI, blood-brain and dermal barriers.