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This book is a questionnaire to record case histories of the acute radiation syndrome in a standardised way. Since the acute radiation syndrome can be considered a rare disease it is deemed necessary to record all accessible case histories world-wide in a standardised form. This questionnaire provides the possibility to describe the signs, symptoms, and therapeutic approaches concerning the acute radiation syndrome. There are few if any comparably comprehensive publications on the acute effects in man of inadvertent exposure to ionising radiation. Completing and returning the questionnaire gives access to the WHO database on the acute radiation syndrome currently built up in Moscow and Ulm. The data in the questionnaire and the database are similar in structure. The database will serve in case of future radiation accidents by providing comparable case histories and for scientific work on the acute radiation syndrome. The questionnaire reflects the conceptual database scheme. It is designed according to ergonomical guidelines and its use is explained by examples.
Produktinformation
Utgivningsdatum1994-02-28
Mått210 x 297 x 8 mm
Vikt364 g
FormatHäftad
SpråkEngelska
Antal sidor114
FörlagSpringer-Verlag Berlin and Heidelberg GmbH & Co. KG
1. General Data on the Irradiated Patient.- 1.1 Demographic Data.- 1.2 Occupation at the Time of the Accident.- 1.3 History at the Time of the Accident.- 1.4 Institutions Involved in Patient Care and Database Recording.- 2. Accident Information and Personal Exposure Conditions.- 2.1 Accident Description.- 2.2 Source of Irradiation.- 2.3 Personal Exposure Conditions.- 3 Clinical Data After Exposure.- 3.1 Primary Reaction.- 3.2 Involvement of the Nervous System and the Eyes.- 3.3 Radiation Induced Lesions of Skin, its Appendices, and Underlying Tissues.- 3.4 Bone Marrow Syndrome and Blood.- 3.5 Radiation Induced Lesions of Gastrointestinal Tract.- 3.6 Organs Especially Sensitive Under Certain Exposure Conditions.- 3.7 Lesions of Other Organs.- 4. Treatment and Drugs.- 4.1 Individual Radiation Protection Measures.- 4.2 Physical Methods of Treatment.- 4.3 Substituting Therapy by Blood and Blood Products.- 4.4 Drugs.- 4.5 Haemostimulators.- 4.6 Haemopoietic Stem Cell Transplantation.- 5. Clinical Status at the Time of Reporting.- 5.1 Survival Status.- 5.2 Clinical Status.- 5.3 Functional Status.- 6. Skin Burns.- 6.1 Burn Score.- 6.2 Localisation Coding - Total Body, Head, Neck and Upper Trunk.- 6.3 Localisation Coding - Arms, Lower Trunk.- 6.4 Localisation Coding - Lower Trunk, Legs.- 6.5 Skin Burns.- 7. Haematopoietic Stem Cell Transplantation.- 7.1 Source of Stem Cells.- 7.2 Type of Transplantation.- 7.3 Histocompatibility Tests for Allogeneic Transplantation.- 7.4 Donor Information.- 7.5 Transplant Manoeuvre.- 7.6 Drugs to Prevent Acute Graft-versus-Host Disease (GvHD).- 7.7 In vitro and in vivo Removal of Donor T Cells to Prevent GvHD.- 7.8 Evidence for Haemopoietic Engraftment.- 7.9 Overall Evaluation of Engraftment.- 7.10 Graft-versus-Host Disease.- 7.11 Specific Therapy for GvHD.- 8. Annexes.- 8.1 IAEA International nuclear event scale.- 8.2 Conversion of Non-SI to SI Units.- 8.3 Orders of Magnitude.- 8.4 Karnofsky Scale for Rating Activity Status.- 8.5 References.- 8.6 Normal Values of Laboratory Parameters.- 8.7 Pages for copying.