Cell Division Machinery and Disease

Häftad, Engelska, 2018

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This book critically evaluates the causal link between cell division machinery and disease. Cell Division Machinery and Disease is essential reading for graduate or advanced graduate students, researchers or scientists working on cell division as well as clinicians interested in the molecular mechanisms of the discussed diseases.

Produktinformation

Utgivningsdatum2018-08-02
Mått155 x 235 x 14 mm
Vikt388 g
FormatHäftad
SpråkEngelska
SerieAdvances in Experimental Medicine and Biology
Antal sidor235
FörlagSpringer International Publishing AG
ISBN9783319860831

Tillhör följande kategorier

Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik
Naturvetenskap:allmänt inom Naturvetenskap och teknik

Monica Gotta is Ordinary Professor at the Medical Faculty of the University of Geneva. She has previously worked as a Swiss-National Science Foundation Professor at the ETH Zurich. Her research interests are the (a)symmetric cell divisions of C. elegans embryos and human cells. She has published 43 papers and 1 book chapter. She has also been awarded an EMBO YIP award.Patrick Meraldi is Associate Professor at the Medical Faculty of the University of Geneva. He has previously worked as a Swiss-National Science Foundation Professor at the ETH Zurich. His research interest is primarily in the field of chromosome segregation in human cells. He has published 49 papers and 2 book chapters. He has also been awarded an EURYI award , an EMBO YIP award and the Walther Flemming Medal.

1.Meiotic divisions: no place for gender equality.- 2.Consequences of centrosome dysfunction during brain development.- 3.Dividing with extra centrosomes: a double edged sword for cancer cells.- 4.Kinetochore malfunction in human pathologies.- 5.The elephant in the room: the role of microtubules in cancer.- 6.Clinical development of anti-mitotic drugs in cancer.- 7.Mitotic dysfunction associated with aging hallmarks.- 8.Unbalanced Growth, Senescence and Aging.- 9.The spindle orientation machinery beyond mitosis: when cell specialization demands polarization.