Cardiac Cellular Electrophysiology

Cardiac Cellular Electrophysiology is for the clinical cardiologist who wishes to refresh or deepen his understanding of the cellular basis of cardiac electrophysiology, and to those researchers interested in the basis of the electrical activity of the heart: researchers, pharmacologists, teachers in physiology, pharmacology and other biomedical studies, and medical students from graduate to postgraduate level. This book is a primer of basic electrophysiology, the cardiac action potential, and the physiological basis of the electrocardiogram. The authors provide the necessary background in cellular electrophysiology to allow accessibility of this material to a wide audience. Edward Carmeliet and Johan Vereecke, Katholieke University Leuven, Belgium, have collaborated for over 30 years in cardiac electrophysiology research. Their studies include the genesis of the normal action potential, its changes in ischaemia, the effect of drugs, and the mechanism of arrhythmias, using techniques from the classic potential registration with intracellular microelectrodes to whole cell clamp and single channel measurements.