Biological and Clinical Landscape of Meningiomas

Gelareh Zadeh is a Professor at the Department of Surgery University of Toronto. She is a Neurosurgeon-Scientist at Toronto Western Hospital, University Health Network. She was most recently appointed as the Wilkins Family Chair in Brain Tumor Research. Her research laboratory is focused on studying the molecular mechanisms of glioma angiogenesis and molecular regulators of tumour metabolism.Rolan Goldbrunner is Professor in the Department of General Neurosurgery and Head of the Center for Neurosurgery at the University of Cologne in Germany. He is the Past President of the German Society for Neurosurgery. His special focus is on brain tumours.Boris Krischek is a Neurosurgeon at Les Hôpitaux Robert Schuman in Luxembourg and Professor in the Department of General Neurosurgery at the University of Cologne in Germany. Farshad Nassiri is a Neurosurgery Resident at University of Toronto and a member of Zadeh Lab.

• Chapter 1. Introduction and History of Meningiomas.- Chapter 2. Clinical Presentation and Prognosis.- Chapter 3. Imaging Characteristics of Meningiomas.- Chapter 4. Histopathology of Meningiomas.- Chapter 5. Skull Base Meningiomas.- Chapter 6. Spinal Meningiomas.- Chapter 7. Surgical Therapies.- Chapter 8. Radiation Therapies.- Chapter 9. Illustrative Cases.- Chapter 10. Advances in CNS Tumor Classification.- Chapter 11. Genomic Landscape.- Chapter 12. Radiation-Induced Meningiomas.- Chapter 13. Meningioma Predisposing Syndromes.- Chapter 14. Epigentic Landscape.- Chapter 15. Immune Profile.- Chapter 16. PDX Models/Mouse Models/Cell Lines.- Chapter 17. Novel Medical Therapies .- Chapter 18. Quality of Life in Menigioma Patients .- Chapter 19. Illustrative Cases: Revisited with Adjuvant Molecular Data .- Chapter 20. Future Directions in Management.