Bioactive Lipids in Health and Disease

Andres Trostchansky is an associate professor of Biochemistry at the University de la Republica in Montevideo, Uruguay. He has received the Roberto Caldeyro Barcia Award in Biology.Homero Rubbo is a professor in the department of Biochemistry at the University de la Republica in Montevideo, Uruguay.

• Prelims.- Diffusion and transport of reactive species across cell membranes.- Characterization of hydroxy and hydroperoxy polyunsaturated fatty acids by mass spectrometry. Understanding Peroxisome Proliferator-Activated Receptors: from the structure to the regulatory actions on metabolism.- Diminishing Inflammation by Reducing Oxidant Generation: Nitrated Fatty Acid-Mediated Inactivation of Xanthine Oxidoreductase. Unfolded protein response: Cause or consequence of lipid and lipoprotein metabolism disturbances?- Arachidonic acid metabolism in macrophages: role of NADPH oxidases.- Lipid Metabolism and Signaling in Platelet Function.- Dyslipidemia in ischemia/reperfusion injury.- Epicardial adipose tissue in cardiovascular disease.- Bioactive Lipids and the gut-brain axis: diet as a modulator of bioactivity and diversity of lipids in the brain.- Nitroalkylation of α-synuclein by nitro-oleic acid: Implications for Parkinson´s disease.- Bioactive lipids in inflammation after central nervous system injury.- Index.