Antiulcer Activity of Lagenaria Siceraria

The present study showed that the Lagenaria siceraria extract possess gastroprotective activity as evidenced by its significant inhibition in the formation of ulcers induced by various physical and chemical agents. A dose response antiulcer study has been done using 100mg/Kg & 200mg/Kg of Lagenaria siceraria extract against various validated gastric ulcer models like Pylorus ligation,Asprin ,Ethanol and Cold restraint stress induced ulcer.The optimal effect was obsereved was at dose of 200mg/Kg of Lagenaria siceraria extract.