Antimicrobial Resistance in the 21st Century

Antimicrobial Resistance in the 21st Century: Understanding and Combating the Rising Threat addresses one of the greatest public health challenges of our time, antibiotic resistance. This book explores the science, history, and global impact of this crisis, providing readers with the knowledge they need to understand the problem and take necessary action. It meticulously unpacks the genetic, biochemical, and evolutionary mechanisms behind antibiotic resistance, while examining how human behaviors-from healthcare practices to agricultural methods-fuel its spread. It highlights the critical roles of environmental factors, misuse of antibiotics, and gaps in diagnosis and stewardship that exacerbate resistance across both clinical and community settings. It also examines innovative solutions, including next-generation antibiotics, alternative therapies, vaccines, and advances in infection control, alongside the global policy strategies necessary to combat this threat. By addressing the scientific, medical, economic, and sociocultural dimensions of antimicrobial resistance, this book provides a roadmap for coordinated, multidisciplinary efforts to preserve antibiotic efficacy and safeguard public health for future generations. It is written by global experts for researchers and scientists in microbiology, infectious diseases, public health, and pharmacology. It is also of interest to healthcare professionals such as clinicians, pharmacists, and nurses, as well as policymakers, public health officials, students, and industry professionals.

• Explains how bacteria develop resistance, the role of overuse and misuse, and why new antibiotics are difficult to develop
• Covers infection control measures, responsible antibiotic prescribing, and global initiatives
• Discusses cutting-edge research on alternatives to antibiotics, such as bacteriophage therapy and artificial intelligence--driven drug discovery