Advances in Pain Research: Mechanisms and Modulation of Chronic Pain

Dr. Bai Chuang Shyu is a principle investigator at the Institute of Biomedical Sciences, Academia Sinica, Taiwan. He served as the chairman of the Asian Pain Symposium, which was held in Taipei in 2017. His research focuses on the neuronal mechanisms underlying the central post stroke and information transmission in thalamocingulate circuitry in vitro. He has published more than 40 research articles in these fields.Dr. Makoto Tominaga is a professor at the National Institutes of Physiological Sciences and National Institutes of Natural Sciences, Japan, where he leads the cell signaling division. His research focuses on regulation and function of TRP channels. Prof. Tominaga has published more than 200 articles in this field.

• Molecular Mechanisms of the sense of touch: an overview of mechanical transduction and transmission in Merkel discs of whisker hair follicles and some clinical perspectives.- TRP Channels in Nociception and Pathological Pain.- Involvement of TRPV1-ANO1 interactions in pain enhancing mechanisms.- Roles of ASICs in Nociception and Proprioception.- Tackling pain associated with rheumatoid arthritis: Proton-sensing receptors.- Intra-Fascicular Local Anesthetic Injection damages Peripheral Nerve Induced Neuropathic Pain.- Microglia in the CNS and neuropathic pain.- Descending noradrenergic inhibition –an important mechanism of gabapentin analgesia in neuropathic pain.- Chronic neuropathic pain protects heart from ischemia reperfusion injury.- Knowing the neuronal mechanism of spontaneous pain to treat chronic pain in future.- Role of Neuroinflammation in Opioid Tolerance: Translational Evidence from Human-to-Rodent Studies.- Neural mechanisms of offset analgesia.- Cortical LTP: A synaptic model for chronic pain.- Pain-associated neural plasticity in the parabrachial to central amygdala circuit.- Electrophysiological signature of pain.- Neuroimaging Studies of Primary Dysmenorrhea.- Brain reward circuit and pain.- The Involvement of P2X7 Receptors and BDNF in the Pathogenesis of Central Post Stroke Pain.- Melatonin: A new-generation therapy for reducing chronic pain and improving sleep disorder-related pain.- Central poststroke pain, comorbidity, and associated symptoms in animal and human models