Toxicity Testing

Steering Committee on Identification of Toxic and Potentially Toxic Chemicals for Consideration by the National Toxicology Program, National Research Council

• 1 FRONT MATTER; 2 EXECUTIVE SUMMARY; 3 INTRODUCTION; 4 PART 1: TOXICITY-TESTING NEEDS IN THE SELECT UNIVERSE; 5 1. INTRODUCTION; 6 2. SAMPLE SELECTION; 7 3. OPERATING POLICIES FOR IDENTIFICATION, ACQUISITION, AND ORGANIZATION OF DATA; 8 4. DATA EVALUATION; 9 5. RESULTS; 10 6. SUMMARY AND CONCLUSIONS; 11 REFERENCES; 12 APPENDIXES; 13 PART 2: SETTING PRIORITIES FOR TOXICITY TESTING; 14 1. INTRODUCTION; 15 2. DESIGN OF THE PRIORITY-SETTING SYSTEM; 16 3. BRIEFLY FOLLOWING A CHEMICAL THROUGH AN ILLUSTRATIVE SYSTEM; 17 4. DETAILED DESCRIPTION OF THE OPERATION OF AN ILLUSTRATIVE SYSTEM; 18 5. FUTURE DEVELOPMENT, IMPLEMENTATION, AND REFINEMENT OF THE SYSTEM; 19 6. CONCLUSIONS AND RECOMMENDATIONS; 20 REFERENCES; 21 APPENDIXES