The Genetic Basis of Common Diseases

• PART 1: APPROACHES ; 1. Approach to Genetic Bases of Common Diseases ; 2. Molecular Genetics of Common Diseases ; 3. Genetic Epidemiologic Methods ; 4. Evolution of Human Genetic Diseases ; 5. Animal Models of Complex Genetic Disease ; 6. Genetic Counselling: History, Risk Assessment, Strategies and Ethical Considerations ; PART 2: CARDIOPULMONARY DISEASES ; 7. Genetics of Coronary Atherosclerosis ; 8. Hypertension ; 9. Chronic Obstructive Pulmonary Disease ; PART 3: IMMUNOLOGIC AND INFECTIOUS DISEASES ; 10. Genetics of Human Susceptibility to Infectious Diseases: Progress and Prospects ; 11. Genetics of Asthma and Bronchial Hyperresponsiveness ; 12. IgA Deficiency and Common Variable Immunodeficiency ; PART 4: GASTROINTESTINAL DISORDERS ; 13. Peptic Ulcer and Gastritis ; 14. Lactase Deficiency: Biological and Medical Aspects of the Adult Human Lactase Polymorphism ; 15. Inflammatory Bowel Disease ; 16. Gallstones ; 17. Chronic Liver Disease ; 18. Hereditary Hemochromatosis ; 19. Gluten-Sensitive Enteropathy ; PART 5: ENDOCRINE DISORDERS ; 20. Thyroid Disease ; 21. Type 1 Diabetes Mellitus ; 22. Type 2 Diabetes Mellitus ; 23. Obesity ; 24. Genetics of Osteoporosis ; 25. Hyperuricemia and Gout ; PART 6: GENITOURINARY DISEASES ; 26. Gynaecologic Disorders ; 27. Infertility and Pregnancy Loss ; PART 7: RHEUMATOLOGIC DISEASES ; 28. Immunology and Immunogenetics ; 29. Rheumatoid Arthritis ; 30. Seronegative Spondyloarthropathies ; 31. Genetics of Systematic Lupus Erythematosus ; 32. Genetic Basis of Primary Osteoarthritis ; 33. Common Disorders of Connective Tissue ; PART 8: CANCER ; 34. Gastrointestinal Cancer ; 35. Breast Cancer ; 36. Familial and Genetic Influences on Risk of Lung Cancer ; 37. Reproductive Organ Cancers ; 38. Skin Cancer ; 39. Prostate Cancer ; 40. Haematologic Cancer ; PART 9: NEUROPSYCHIATRIC DISORDERS ; 41. Epilepsy ; 42. Multiple Sclerosis ; 43. Alzheimer's Disease ; 44. Affective Disorders ; 45. Schizophrenia ; 46. Alcoholism ; 47. Mental Retardation ; 48. Hereditary Hearing Loss ; 49. Migraine ; PART 10: OTHER COMMON PROBLEMS ; 50. Common Skin Disease ; 51. Genetic Modulation of Aging and Longevity ; 52. Mitochondrial Defects in Common Diseases ; 53. Constitutional Chromosome Disorders in Adults ; PART 11: THERAPY ; 54. Genetic Consequences of Modern Therapeutics: Iatrogenic Mutagenesis ; 55. Pharmacogenetics, Ecogenetics and Pharmacogenomics

This book is an excellent starting point for clinicians, clinical geneticists and epidemiologists to cover the principles and specifics on the genetic aspect of common diseases of the Western world. For any of the diseases described, it will give the reader a basis from which to launch into a more in depth study.