bokomslag The effects of erythropoietin on telomerase in malignant cells
Vetenskap & teknik

The effects of erythropoietin on telomerase in malignant cells

Orit Uziel Gil Kanfer Meir Lahav

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  • 52 sidor
  • 2014
The study described in this book presents the effects of erythropoietin on Telomerase activity and regulation in malignant and non- malignant non-erythroid cells. Erythropoietin's exposure upregulates telomerase activity in a post translational level by the Lyn/SRC AKT axis. Inhibition of telomerase that shortens telomeres abolished that effect, suggesting that erythropoietin's treatment might be given with anti- telomerase compounds to minimize the upregulation of telomerase in the cancer cells.
  • Författare: Orit Uziel, Gil Kanfer, Meir Lahav
  • Format: Pocket/Paperback
  • ISBN: 9783659515828
  • Språk: Engelska
  • Antal sidor: 52
  • Utgivningsdatum: 2014-07-03
  • Förlag: LAP Lambert Academic Publishing