Vetenskap & teknik
Pocket
The effects of erythropoietin on telomerase in malignant cells
Orit Uziel • Gil Kanfer • Meir Lahav
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The study described in this book presents the effects of erythropoietin on Telomerase activity and regulation in malignant and non- malignant non-erythroid cells. Erythropoietin's exposure upregulates telomerase activity in a post translational level by the Lyn/SRC AKT axis. Inhibition of telomerase that shortens telomeres abolished that effect, suggesting that erythropoietin's treatment might be given with anti- telomerase compounds to minimize the upregulation of telomerase in the cancer cells.
- Format: Pocket/Paperback
- ISBN: 9783659515828
- Språk: Engelska
- Antal sidor: 52
- Utgivningsdatum: 2014-07-03
- Förlag: LAP Lambert Academic Publishing