The Basis of Toxicity Testing

This substantially updated edition presents fundamental principles and concepts behind the various types of toxicological studies, and explains how to design and conduct studies and interpret results. It explains the increasing need to monitor, assess, and reevaluate the toxicity database of many agents and evaluates the place of individual studies in the overall toxicological assessment of a chemical. Concise descriptions of the formats of in vivo and in vitro studies and methods used in assessing endpoints of toxicity make this an essential introduction and guide to understand or conduct toxicological studies. The second edition includes information on a variety of new alternative testing protocols and the new EEC regulations of the new in vitro alternative testing procedures.