Sepsis

Sepsis, a leading cause of death, describes a complex clinical syndrome that develops when initial, appropriate host response to an infection becomes amplified and then dysregulated, not only does the disease progress in various phases, but initial inflammation is sometimes followed by immunosupression. Also a multitude of microorganisms are involved in sepsis pathology. The present treatment regimens available for sepsis are limited, adjunct herbal therapy to already established therapies seems to be the need of hour. The present book describes the general pathobiology of sepsis, followed by the treatment strategies presently in vogue, the different signaling pathways involved, and ultimately reviews some of the plant based components that might be tested as complement to present therapies.