Replicative Cessation & DNA Damage in Human Fibroblast Under Stress 1
bokomslag Replicative Cessation & DNA Damage in Human Fibroblast Under Stress
Kropp & själ

Replicative Cessation & DNA Damage in Human Fibroblast Under Stress

Sahar Khalil • Gehad Hammouda • Somaya Hosny

Pocket

1499:-

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  • 204 sidor
  • 2011
Aging can be viewed partly as a degenerative process dictated by free radical reactions. Human diploid fibroblasts (HDFs) lose the capacity to proliferate and enter a state termed replicative senescence after a finite number of population doublings in vitro. Presenescent human fibroblasts, when treated with a sub-lethal dose of H2O2, enter long term growth arrest resembling replicative senescence. H2O2 induced growth arrest; p53 protein expression and the effect of vitamin C as an antioxidant were determined in this study.
  • Författare: Sahar Khalil, Gehad Hammouda, Somaya Hosny
  • Format: Pocket/Paperback
  • ISBN: 9783846553268
  • Språk: Engelska
  • Antal sidor: 204
  • Utgivningsdatum: 2011-12-22
  • Förlag: LAP Lambert Academic Publishing

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