Proceedings of the Fourth USSR-FRG Symposium Tbingen, Federal Republic of Germany June 812, 1982

Frontmatter -- PREFACE -- CONTENTS -- PEPTIDE SYNTHESIS AND ANALYTICAL PROBLEMS OF SYNTHETIC PEPTIDES -- Enzyme-Catalyzed Semisyntheses with Porcine Insulin -- Preparation, Properties and Application of Photo- Reactive Insulins -- Synthesis of A19-[3,5-Diiodo-Tyrosine] Porcine Insulin -- Semisynthesis of Linear Proinsulin Analogues with Shortened C-Peptides -- Synthesis of Unsymmetrical Cystine Peptides: Directed Disulfide Pairing with the Sulfenohydrazide Method -- Synthesis of Mid Regional Parathyrin Segments -- Application of Modern Methods in the Synthesis of Cyclic Analogues of Bradykinin -- Total Synthesis of Neurotoxin II from Naja Naja Oxiana Cobra Venom -- The Synthesis of the N-Terminal Amino Acids of the Peptide-Nucleoside Antibiotic Nikkomycin and their Use in Peptide Synthesis -- Synthesis and Activity of Peptides Analogues to the Toxic Peptides Isolated from Amanita Virosa Mushrooms -- Synthesis of a New Photolabile Tritiated Antamanide- Analogue -- Synthesis and Properties of (NLe56'60 ) 34-65 Bacteriorhodopsin Fragment -- Synthetic Peptide Derivatives of Bacterial Lipoprotein and their Interaction with Lymphocyte Plasma Membranes -- Syntheses of Defined Peptide Derivatives by Aminolysis of 3-[N -Benzyloxycarbonyl Peptidyloxy]-2-Hydroxy-NMethyl- Benzamides at Elevated Temperatures II. Synthesis of the Peptide Derivatives Z-Ala-X-Gly-N(Et)2, X=Phe, Leu, Val, Ser (But), Glu (OBut) -- Recently Developed Amino Protecting Groups -- Syntheses and Reaction of Peptide Cyclols -- Synthesis of Cyclic Tripeptides Containing CONH Groups -- Conformational Preferences of Model Peptides and their Impact in Peptide Synthesis -- Analytical Studies on Side Products in the Synthesis of Secretin -- High Performance Liquid Chromatography of Protected Peptides -- Field Desorption Mass Spectra and Fast Atom Bombardment Spectra of Partially Protected Peptides -- STRUCTURAL FEATURES OF PEPTIDES AND PROTEINS -- Isolation and Structural Analysis of a New Neuropeptide, the Head Activator -- Biochemical, Biological and Immunological Characterization of Bovine Nerve Growth Factor -- Embryonic Haemoglobins in Mammals Haemoglobin Components in Human and Pig Embryos; Primary Structures of the Human and Pig-Chains and their Phylogenetic Relationship to the a-Chains -- The Complete Primary Structure of Elongation Factor G from E-coli -- The Primary Structure of E.coli RNA Polymerase. Nucleotide Sequence of the rpoC Gene and Amino Acid Sequence of the ß'-Subunit -- Determination of Amino Acid Sequences of Large Hydrophobic Peptides of Rhodopsin -- Three-Dimensional Structure of Actinoxanthin at High Resolution -- Primary and Secondary Structures of Peptides which Form Voltage-Dependent Pores in Lipid-Bilayers -- Purification and Characterization of a Second Retinal Binding Protein in Halobacterium Halobium -- Homo- and Heteronuclear Two-Dimensional NMR Spectroscopy of Cyclic Peptides -- MISCELLANEOUS AND BIOLOGICAL ACTIVITY OF PEPTIDES AND PROTEINS -- Bioorganic Chemistry of Rhodopsins -- The Role of Tyrosine 26 and Tyrosine 64 in Bacteriorhodopsin Function -- Structure-Function Studies on Gastrin Related Peptides -- Analogues of Angiotensin with Vasodepressor Activity -- Regulatory Influence of Peptide Hormones on Neural Cells in Culture -- Enzyme Immunoassay of Human Urinary Kallikrein -- The Alamethicin Pore is Formed by a Voltage-Gated Flip-Flop of ?-Helix Dipoles -- Conformations of the Transmembrane Channel Formed by Gramicidin A -- Study of Veratridine Receptors Associated with Sodium Channels -- The Role of Neurotoxins in Studying Sodium Channels -- Structure and Mechanism of Action of Neurotoxins from the Venom of Latrodectus Spiders -- Topography of the Acetylcholine Receptor - Neurotoxin Binding Sites Probed by Spectroscopy and Photolabeling -- Peptides as Iron Ionophores (Siderophores) -- Interaction of Proteinases and their Protein Inhibitors as Studied by the Spin-Label Technique -- An Inhibitor of Elastase from Anemonia sulcata