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Neurobiology of Addiction highlights some of the most promising research areas of the rapidly expanding field of addiction. It will be useful as a practical tool for clinicians, research investigators, and trainees-both in addiction and in other illnesses with overlapping mechanisms-as well as an informative resource for non-technical readers who are interested in addiction or mental health policy. The editors have combined their areas of expertise to provide a unique perspective into the prevention and treatment of addictive disorders. Their approach addresses addiction in the broader context of behavioral processes and survival-related adaptations, focusing on its neurobiological precursors and drawing parallels between addictions and other recurrent or progressive psychiatric disorders. The book also emphasizes resilience, clinical contexts of addictive behavior, and treatment strategies that target its underlying neurobiological mechanisms.
Professor Alan C. SwannProfessor and Vice-Chair for Research and Co-Director, Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, the University of Texas Health Science Center at HoustonProfessor F. Gerard MoellerProfessor and Vice-Chair for Translational Research and Director of the Center for Neurobehavioral Research on Addictions, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston
PrefaceContributors 1. Beyond Drugs: Addictions in the Context of Recurrent/Progressive Psychiatric IllnessAlan C. Swann 2. Behavioral Mechanisms in AddictionMargaret C. Wardle, Jin H. Yoon, Anka A. Vujanovic, Michael F. Weaver, Scott D. Lane, and Joy M. Schmitz 3. The biology of nicotine addiction and factors that differentiate youth who smoke from those who do notFelicia R. Carey and Anna V. Wilkinson 4. Resilience and Opiate MisuseSameer Hassamal, Divya Ramesh, and F. Gerard Moeller5. Alcohol-Related Disorders: Adaptations and Progression to Disordered DrinkingTherese A Kosten, Colin Haile, Marijn Lijffijt, and Alan C. Swann6. The Neurobiology of Behavioral SensitizationJeffery D. Steketee7. Stress and AddictionMarijn Lijffijt8. The Neurobiology of Behavioral Addictions: Sexual AddictionDonald L. Hilton, Jr., Stefanie Carnes, and Todd L. Love9. Norepinephrine as a therapeutic target for cocaine-use disorderColin N. Haile, Thomas F. Newton, and Thomas R. Kosten10. Cannnabis, endocannabinoids, and mechanisms of addictionChristopher Rodgman and Christopher D. Verrico11. Cocaine addiction therapy pharmacogenetics David A. Nielsen12. Increasing the Information Yield from Clinical Trials in Addictions: Bayesian Statistics, Adaptive Designs, and Biomarker EvaluationCharles Green, Robert Suchting, Nuvan Rathnayaka, Margaret C. Wardle, and Joy M. Schmitz13. Mechanisms of Sensitization to Stress, Affective Episodes, and Abused Substances: Implications for Treatment and PreventionRobert M. Post