Vetenskap & teknik
Pocket
Molecular mechanisms of photo-oxidative damage in cells
Aldwin Suryo Rahmanto • Lecturer In English Michael Davies
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Living organisms are continually exposed to oxidants. During oxidative stress, reactions of oxidants with biological macromolecules can result in both direct damage and the formation of long-lived, reactive, hydroperoxides. The series of studies undertaken in this work focused on the early cellular events following generation of reactive singlet oxygen (1O2) and identified that long-lived protein hydroperoxides, a major product of protein oxidation, can play a significant role in cellular damage by selectively targeting both low-molecular mass and protein thiols. These findings are invaluable in providing an insight of the early molecular events of oxidative stress and a cornerstone for future research in developing a better strategy to prevent oxidative damage.
- Format: Pocket/Paperback
- ISBN: 9783844327120
- Språk: Engelska
- Antal sidor: 284
- Utgivningsdatum: 2011-04-08
- Förlag: LAP Lambert Academic Publishing