Immunnoendokrinnye Vzaimodeystviya Pri Khsn Razlichnogo Geneza

KhSN - naibolee chastoe oslozhnenie vsekh organicheskikh bolezney serdtsa i ryada khronicheskikh zabolevaniy vnutrennikh organov. KhSN otmechaetsya ne menee chem u 1% vzroslogo naseleniya, a u lits starshe 75 let - u 10%. V poslednie gody vse bol'shee vnimanie issledovateley i klinitsistov obrashchaetsya k immunologicheskim aspektam patogeneza KhSN. Novym aspektam patogeneza KhSN i ateroskleroza posvyashcheno mnogo rabot inostrannykh i otechestvennykh uchyenykh. Odnako v nikh izuchaetsya obychno tol'ko odin aspekt problemy (immunologicheskiy, endokrinnyy). Tsel'yu dannoy raboty bylo izuchit' neyroimmunoendokrinnye vzaimodeystviya pri razlichnykh stadiyakh KhSN ishemicheskogo i revmaticheskogo geneza. Byli polucheny interesnye rezul'taty po svyazi urovnya izuchennykh pokazateley (FNO-, IL-6, MNUP, katekholaminov ) s tyazhest'yu klinicheskogo sostoyaniya bol'nogo, a takzhe v zavisimosti ot geneza KhSN. Pokazano dostovernoe otlichie ukazannykh pokazateley pri KhSN ishemicheskoy i neishemicheskoy (RBS) prirody. Vpervye provedyen sravnitel'nyy analiz dannykh po tsennosti i informativnosti razlichnykh klassifikatsiy KhSN.