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Guoku Hu, Huangui Xiong, Shilpa Buch - HIV-Associated Neurocognitive Disorders, Häftad

Häftad, Engelska, 2024

HIV-Associated Neurocognitive Disorders

Av Guoku Hu, Huangui Xiong, Shilpa Buch

3339 kr

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Beskrivning

HIV-Associated Neurocognitive Disorders (HAND) presents a complex and evolving challenge in the context of HIV-1 infection and treatment. This comprehensive volume dives into the clinical manifestations, molecular and cellular mechanisms, and therapeutic strategies underlying HAND and its associated comorbidities. This book brings together cutting-edge research and clinical insights, making it an essential resource for researchers, clinicians, and students engaged in HIV-related studies and neurocognitive research. This resource also aims to advance our understanding of HAND to contribute to the development of novel diagnostic tools and therapeutic interventions for improved patient outcomes.



  • Provides an in-depth exploration of the clinical manifestations of HAND and its comorbidities
  • Includes detailed assessments of the molecular and cellular mechanisms underlying HAND symptoms
  • Examines animal models for studying HAND, including macaque and rodent models
  • Presents insights into epigenetic regulation and signaling pathways implicated in HAND
  • Covers prevention, therapeutic strategies, and diagnostic approaches
Produktinformation
  • Utgivningsdatum: 2024-02-27
  • Mått: 216 x 276 x 32 mm
  • Vikt: 1 770 g
  • Format: Häftad
  • Språk: Engelska
  • Antal sidor: 652
  • Förlag: Elsevier Science
  • ISBN: 9780323997447
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Mer information

Dr. Hu is an Associate Professor in the Department of Pharmacology and Experimental Neuroscience at University of Nebraska Medical Center. His work is focused on mRNA biology, with the ultimate goal of elucidating their functional aspects in drug addiction, and also to identify novel therapeutic strategies that could enhance neuronal function and survival in patients afflicted with these disorders. Dr. Xiong is a Professor in the Department of Pharmacology and Experimental Neuroscience at University of Nebraska Medical Center and leader of the University of Nebraska Medical Center Neurophysiology Laboratory in the Center for Neurovirology and Neurodegenerative Disorders. He is a neuroelectrophysiologist working in the field of NeuroAIDS (the neurological complications of AIDS), which include neurocognitive impairment and HIV-associated dementia (HAD). Current research in his laboratory studies molecular and cellular mechanisms underlying HIV-1-associated cellular and synaptic dysfunction and injury, with the ultimate goal of identifying potential target(s) for the development of therapeutic strategies. Dr. Xiong is the author of Current Laboratory Methods in Neuroscience Research (Springer) and has additionally authored many book chapters. Dr. Buch is a Professor and Executive Vice-Chair of the Department of Pharmacology and Experimental Neuroscience at University of Nebraska Medical Center. Her research focuses on understanding the neuropathogenesis of HIV/SIV infection using cell culture, rodents and macaques as model systems. She is the director of the Nebraska Center for Substance Abuse Research, the mission of which is to promote and enhance drug abuse research and mentor trainees in this area. Dr. Buch is a Member of the European Academy of Sciences, and a Member of the Royal Academy of Belgium.

Recensioner i media

*4 stars* "...a comprehensive and insightful volume that delves into the complex and evolving challenges posed by HIV infection and its impact on neurocognitive functions.... [P]rovides a thorough, up-to-date, and practical guide to understanding and managing HAND and provides valuable insights into a complex and often under-recognized aspect of HIV care. [An] invaluable resource for students, and anyone involved in the care of individuals with HIV or interested in the neurological aspects of infectious diseases.... [P]rovides a better understanding of the neurological complications of HIV/AIDS, [and] a comprehensive yet concise review of a dynamic field with an interdisciplinary approach.... I highly recommend it to clinicians and researchers who are interested in the interplay between the central nervous system and HIV infection." --©Doody’s Review Service, 2024, Sarah M Stuccio, MD (Thomas Jefferson University)

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