Efficacy of Amlexanox in the Treatment of Recurrent Aphthous Ulcers -a Review

There have been many attempts over the years to find an effective treatment for Recurrent aphthous stomatitis (RAS). The treatment consists of therapeutic measures to suppress the symptoms rather than bringing about a definitive cure. The therapeutic choice depends on the severity of the disease, including the frequency of ulcer recurrence, the number of ulcers present, their location and duration, and level of associated or facial pain. Cases of severe RAS, those with painful ulcers, and those that show a high frequency of recurrence usually require systemic therapy. The use of immunosuppressive and anti-inflammatory drugs has demonstrated varying degrees of success in severe cases of RAS.Therefore, the aim of this textbook is to explore and evaluate the efficacy of amlexanox for the treatment of recurrent aphthous ulcers.