Kropp & själ
Pocket
Effects of SIGMA Receptor Ligands in Mammalian Myocardium
Kate Ina Fialov • Marie Nov Kov • Marie Novakova
1109:-
Uppskattad leveranstid 7-11 arbetsdagar
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The history of natural as well as medical sciences is full of fascinating stories: some discoveries were caused by mistake and some were actually not firstly perceived as new findings. Discovery and detailed research of sigma receptors belong to such stories undoubtedly. It is a terminated tale - the endogenous ligand was discovered, even if most recently. On the contrary, still some tesseras are missing in this complicated mosaic which such new receptor system represents: it still remains unclear what is their primary role in biological systems and in their regulation. This review is focused on cardiovascular effects of typical representatives of sigma receptor ligands and - at the same time clinically widely used antipsychotics - haloperidol and perphenazine. Use (or even abuse) of various antipsychotics represents worldwide trend within last few decades and thus studies focused on their side effects become a high priority. Moreover, cardiovascular system disorders belong to the most common causes of morbidity and mortality in the developed countries. A significant group of these disorders is represented by side effects of non-cardiovascular drugs.
- Format: Pocket/Paperback
- ISBN: 9783844382334
- Språk: Engelska
- Antal sidor: 156
- Utgivningsdatum: 2011-06-14
- Förlag: LAP Lambert Academic Publishing