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Microtubule-interfering agents are compounds which affect microtubules network. They found use in cancer therapy (vinblastine, paclitaxel) or as anti-inflammatory agents (colchicine). Present work focuses on the effect of these compounds in signalling of aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor regulating expression of many genes, some of them being involved in biotransformation of carcinogens.
- Format: Pocket/Paperback
- ISBN: 9783659180224
- Språk: Engelska
- Antal sidor: 100
- Utgivningsdatum: 2012-07-17
- Förlag: LAP Lambert Academic Publishing