Dizregulyatsiya Metabolicheskikh Funktsiy Legkikh

Aktual'nost' issledovaniy, predstavlennykh v monografii, opredelyaetsya vysokoy chastotoy legochnykh oslozhneniy u bol'nykh s patologiey golovnogo mozga razlichnogo geneza. Narusheniya metabolicheskikh funktsiy legkikh chasto predshestvuyut nesostoyatel'nosti gazoobmena i operezhayut kliniku razvernutoy dykhatel'noy nedostatochnosti. V rabote na osnove obshirnogo eksperimental'nogo materiala obosnovana patofiziologicheskaya kontseptsiya roli struktur limbiko-dientsefal'noy sistemy mozga, ikh afferentnykh i efferentnykh zven'ev v patogeneze rasstroystv negazoobmennykh funktsiy legkikh. Provedena otsenka stepeni integratsii metabolicheskikh protsessov legochnoy tkani i opredeleny prioritetnye napravleniya rasstroystv negazoobmennykh funktsiy legkikh v usloviyakh limbiko-dientsefal'noy dizregulyatsii. Poluchennye dannye mogut otkryt' novye vozmozhnosti interpretatsii izmeneniy, nablyudaemykh v sisteme vneshnego dykhaniya pri disfunktsii limbicheskikh struktur i stat' teoreticheskoy osnovoy dlya razrabotki nauchno-obosnovannykh mer profilaktiki i korrektsii narusheniy metabolicheskikh funktsiy legkikh v usloviyakh dizregulyatornoy patologii.