Diagnostika tseliakii u vzroslykh

Tseliakiya - eto sistemnoe immunoposredovannoe zabolevanie, vyzyvaemoe glyutenom u geneticheski vospriimchivykh lits. V mire tseliakiey stradaet okolo 1% naseleniya. Klassicheskaya forma zabolevaniya kharakterizuetsya razvitiem sindroma mal'absorbtsii, obuslovlennogo atrofiey slizistoy obolochki tonkoy kishki, odnako tseliakiya mozhet takzhe manifestirovat' shirokim spektrom vnekishechnykh proyavleniy ili protekat' bessimptomno, chto sushchestvenno zatrudnyaet vyyavlenie zabolevaniya. V nastoyashchee vremya na kazhdyy diagnostirovannyy sluchay tseliakii prikhoditsya 4-5 nediagnostirovannykh. Diagnostika tseliakii stroitsya na analize klinicheskoy kartiny i faktorov riska, vyyavlenii spetsificheskikh antitel, endoskopicheskoy i gistologicheskoy kharakteristike slizistoy obolochki tonkoy kishki, otsenke reaktsii na isklyuchenie ili vvedenie v ratsion glyutena. Tseliakiya trebuet differentsial'noy diagnostiki s drugimi zabolevaniyami, proyavlyayushchimisya khronicheskoy diareey, v tom chisle i s funktsional'nymi rasstroystvami kishechnika. V monografii podrobno izlozheny sovremennye podkhody k diagnostike zabolevaniya, a takzhe predstavleny dannye original'nogo issledovaniya, posvyashchennogo diagnostike i differentsial'noy diagnostike tseliakii.