Alan S. Maisel is a Professor of Medicine at the University of California, San Diego (UCSD). He is the Director of the Coronary Care Unit and Heart Failure Program at the VA San Diego Healthcare System in La Jolla, California. Dr. Maisel is active on the faculty at UCSD where he has won numerous teaching awards. Dr Maisel is considered one of the world’s experts on cardiac biomarkers and has over 300 scientific publications. He has authored several ground-breaking publications that have paved the way for development of diagnostic tools for patients with congestive heart failure. In particular, he was the leading investigator on studies that brought the use of BNP into clinical practice. Dr Maisel is also a writer of medical fiction. His first novel, Bedside Manners was optioned to Warner Brothers. His second novel, Brain Chicane, is about a young and idealistic physician working at the premier multiple-organ transplant hospital in Chicago where he investigates overdose cases that are not totally kosher. Allan Jaffe is Professor of Medicine and Professor of Laboratory Medicine and Pathology and Chair of the Division of Core Clinical Laboratory Services at Mayo. He continues as an active clinician in the CCU. Dr. Jaffe has national and international repute for his work in cardiac biomarkers and co-ordinates the Biochemistry group of the taskforce for the Universal Definition of AMI. He is on the editor boards of most of the major cardiology journals and the most prestigious laboratory medicine one (Clinical Chemistry) as well. He has over 500 publications, mostly in the field of biomarkers and cardiac troponin.