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For centuries we have known that fruit is important for health, but we are only just beginning to fully understand why. Bioactives in Fruit: Health Benefits and Functional Foods aims to summarise some of our current knowledge on the bioactive compounds that are associated with the health benefits of specific fruits with a strong emphasis on the validation of health benefits by human intervention trials. Reflecting the current interest in food and health, the book includes strategies to retain and enhance the bioactives in fruit through breeding, growing conditions, fruit storage, processing into ingredients and production of functional foods. To accomplish this task authors with expertise in biology, chemistry, pharmacology, food science, nutrition, medicine, and horticulture have contributed. They come from universities, government and industry funded research institutes and biotechnology and food companies in Europe, the United States, Asia and New Zealand to give the book a broad perspective.This book, describing fruit bioactives, their health benefits when consumed as a food and related topics regarding their development into fresh or processed functional foods, will be of use to postgraduatestudents, researchers, functional food product developers, food regulators and anyone who has curiosity about why fruit is good for you. The information contained within will provide plant breeders with new targets for the development of value-added horticultural products, and will also provide nutritionists and dieticians with a useful resource for developing strategies to assist in preventing or slowing disease onset or severity. Bioactives in Fruit: Health Benefits and Functional Foods is a major resource which will be required reading for anyone working in the fields of health and functional foods.
Margot Skinner is a Professor in Food Science, School of Chemical Sciences and Institute of Plant and Food Science, University of Auckland, Auckland, New Zealand.Denise Hunter is a Research Scientist in Food Innovation at Plant & Food Research Ltd, Auckland, New Zealand.
Contributors xvPreface xxi1 Introduction to the Major Classes of Bioactives Present in Fruit 1Anusooya GnanavinthanBioactives 1Classification of plant-derived bioctives 1Bioactives in fruits 12Conclusion 14References 142 Fibre in Fruit 19Bronwen G. SmithIntroduction 19Dietary fibre 19Fruit 20Plant tissues and types of cell walls 20Cell wall polysaccharides 21Effects of cooking or processing on cell wall composition 25Health benefits 26Future considerations for health functionality 27References 283 Bioavailability of Antioxidant Compounds from Fruits 35Iris F.F. Benzie and Sissi Wachtel-GalorIntroduction 35Antioxidants in fruits 36Factors that affect antioxidant response to ingestion of fruit: ‘apparent’ and ‘real’ bioavailability 42Getting to the end: a note on colonic metabolites 51Finally, increasing bioavailability of antioxidants: can it and should it be done? 51Conclusions 53Acknowledgements 54Declaration of interest 54References 544 Pharmacokinetic and Pharmacodynamic Interaction of Functional Foods with Medicines 59Shizuo Yamada, Yuko Taki, Shingen Misaka, Takashi Okura, Yoshiharu Deguchi, Keizo Umegaki, Hiroshi Watanabe, Yasuo Watanabe and Margot SkinnerIntroduction 59Fruits 60Ginkgo biloba extract (GBE) 63Green Tea 68Saw palmetto extract (SPE) 72Conclusions 73Acknowledgements 74References 745 Health Properties of Apple and Pear 81Richard Espley and Stefan MartensIntroduction 81The origin of apples 81Domestication of apples 82Apple production 82Major classes of apple bioactives 82Biosynthesis and genetic regulation of apple bioactives 86Apple and human health 88Storage and processing 93Strategies to improve the bioactive content of apples 93Conclusions 94References 946 Orange and Grapefruit Bioactive Compounds, Health Benefits and Other Attributes 101Paul F. CancalonIntroduction 101Composition of citrus 102Bioavailability and metabolization of citrus phytochemicals 102Citrus and specific ailments 103Attributes of citrus having raised disproportionate concerns 111Conclusions 116References 1177 Health Benefits from Pomegranates and Stone Fruit, Including Plums, Peaches, Apricots and Cherries 125Francisco A. Tom´as-Barber´an, David Ruiz, Daniel Valero, Diego Rivera,Conchita Ob´on, Catalina S´anchez-Roca and Mar´ıa I. GilIntroduction 125The origin, diversity and traditional uses of the pomegranate (PUNICA GRANATUM L.) 125The origin, diversity and traditional uses of the stone fruits (PRUNUS L.) 126Phytochemical composition 128Effect of processing and storage on pomegranate and stone fruit bioactives 138Health effects of pomegranates 149Health effects of stone fruit 151Conclusion 158References 1598 The Potential Health Benefits of the Subtropical Fruits Kiwifruit, Feijoa and Tamarillo 169Stephen J.M. Skinner, Denise Hunter, Suengmok Cho and Margot SkinnerIntroduction 169Kiwifruit 169Feijoa 182Tamarillo 186Conclusion 187References 1889 Effect of Health-promoting Properties of Grapes, Including Resveratrol 197Susan S. Percival and Robin L. WestIntroduction 197Bioavailability and metabolic fate of compounds 198Heart health benefits and potential mechanisms of action 200Immunity 205Cancer 206Obesity, metabolic syndrome and diabetes 207Cognition 208Conclusion 211Acknowledgements 211References 21110 Potential Health Benefits of Blackcurrants 215Rosalind Miller, Sophie Putnam, Michael Edwards, Gary Woodward and Colin KayIntroduction 215Bioactivity of anthocyanins and metabolites 224Future direction of research 237List of abbreviations 237References 23811 Overview of the Health Properties of Blueberries 251Carrie M. Elks, Joseph Francis, April J. Stull, William T. Cefalu, Barbara Shukitt-Hale and Donald K. IngramIntroduction 251Bioactive components of blueberries 251Obesity and insulin resistance 253Type 2 diabetes mellitus 254Cardiovascular diseases 256Cancer 259Longevity 261Neuroprotection and aging 262Gastrointestinal diseases 266Vision 266Conclusion 267References 26812 Cranberry Polyphenols in the Promotion of Urinary Tract, Cardiovascular and Emerging Health Areas 273Kerrie L. Kaspar and Christina KhooIntroduction 273Bioactives in cranberry 274Health benefits of cranberry 277Conclusion 286References 286Further Reading/Resources 29213 Vegetable Fruits: A Cornucopia of Health Benefits 293Carolyn E. ListerIntroduction 293Tomatoes 300Capsicum 310Other solanaceous vegetable fruits 317Cucurbitaceae 319Other vegetable fruits 324Conclusions 325References 326Further Reading/Resources 33414 Potential Health Benefits of Avocados 337Donald K. Ingram, Carrie M. Elks, Gary M. Davenport and George S. RothIntroduction 337Antioxidant properties 339Cardiovascular and metabolic disease 339Osteoarthritis/Bone health 341Inflammation 343Cancer 344Neuroprotection 345Wound healing 345Aging 345Toxicity 347Conclusions 348References 34815 Cardiovascular Benefits of Olive Oil: Beyond Effects of Fat Content 353Elena M. Yubero-Serrano, Antonio Camargo Garcia, Jose Lopez-Miranda and Francisco Perez-JimenezIntroduction 353Factors affecting phenol compound content in VOO 355The health effect of VOO 357Conclusion and future perspectives 361Acknowledgements 362References 36216 Cocoa, Blood Flow and the Brain 367Crystal F. Haskell and Anthony W. WatsonIntroduction 367Cultivation and extraction 367Active components 368Pharmacokinetics and absorption 369Mechanism of action 371Human intervention trials 372Epidemiological evidence 380Conclusions 381References 38417 Breeding for Enhanced Bioactives in Berry Fruit 389Alastair Currie, Jessica Scalzo and Bruno MezzettiIntroduction 389Breeding berry fruit for improved bioactives 392Use of genetic engineering for improving bioactive compounds 400Conclusions 403References 40318 The Influence of Pre- and Postharvest Environmental Stress on Fruit Bioactives 409David J. BurrittIntroduction 409The main groups of fruit bioactives sensitive to environmental stressors and their associations with human health 410The main environmental stressors that can influence the levels of bioactives in fruits 413The influence of environmental stressors and other treatments on the levels of bioactives in some commercially important fruits 416Xenohormesis: an ancient response with modern applications 421References 42219 Recovery of Valuable Bioactives from Residues Arising from Fruit Processing 429Zaid Saleh, Reinhold Carle and Dietmar Rolf KammererIntroduction 429Membrane separation and filtration 432Adsorption and ion exchange processes 444Summary 461Nomenclature 461References 46220 Stability and Bioaccessibility of Fruit Bioactives in Foods: Food Component Interactions and Matrix Effect 467Dongxiao Sun-WaterhouseIntroduction 467Key components present in fruit-based functional foods 468Interactions between fruit bioactives and other food components in various food systems 477Conclusion and future outlook 498References 499Index 509
“Bioactives in Fruit: Health Benefits and Functional Foods is a major resource which will be required reading for anyone working in the fields of health and functional foods.” (Biotechnology, Agronomy, Society, Environment, 1 October 2013)