An In-Vitro Study

In vitro urolithiasis has been performed on the selected plant Uraria picta by using the standard drug, Neeri. The work was accomplished by simple in vitro antiurolithiatic model. In this method percentage dissolution of laboratory prepared kidney stone was measured which can be similar to the stone formed in human kidney. Ethanolic leaf extract of Uraria picta shows dissolution nearer to the standard drug Neeri and aqueous extract have little lower activity then the ethanolic extract. In another method using artificial urine, with inhibitor & without inhibitor it was found that both extract have significant antiurolithiatic activity. This study has given primary substantiation for Uraria picta as the plant possess antiurolithiatic property.