Adverse effects of Amiodarone

Arrhythmia is a problem with rate or rhythm of the heartbeat. In arrhythmia heart can beat too fast or too slow or with an irregular rhythm. The formation and conduction of electro cardio signals and the synchronous contraction of atria and ventricles with rhythmicity are both triggered and regulated by the cardiac conduction system. Defect of this electro cardio conduction will lead to various types of cardiac arrhythmias An electrical potential exists across the cell membrane that changes in a cyclic manner related to the flux of ions across the cell membrane, principally K+, Na+, and Ca2+. If the change in the membrane potential is plotted against time in a given cycle of a His-Purkinje fiber,a typical action potential results